Usage Information
Citation Information: J Clin Invest. 1971;50(11):2414-2425. https://doi.org/10.1172/JCI106740.
Abstract
Extracellular fluid volume expansion with isotonic saline (7.5% of body weight) decreased maximum glucose reabsorption rate by rat kidneys at plasma glucose concentrations greater than 30 mM. Glucose reabsorption rate was 30.2 ±1.6 (SE) μmoles/min·g kidney in nonexpanded rats; it was 18.4 ±1.5 μmoles/min·g in volume-expanded rats. Glucose reabsorption determined by micropuncture was 92% complete at the end of accessible superficial proximal convolutions. Volume expansion resulted in a slight but statistically insignificant reduction of maximal glucose reabsorption rate in superficial nephrons from 786 ±35 μμmoles/min·g kidney in nonexpanded rats to 720 ±30 μμmoles/min·g in volume-expanded rats. Superficial nephron filtration rate was increased by volume expansion from 28.8 ±1.2 nl/min·g to 36.6 ±1.5 nl/min·g kidney. In nonexpanded rats, the ratio of glucose reabsorption to glomerular filtration (tmg/sgfr) was similar in superficial and juxtamedullary nephrons. In volume-expanded rats superficial nephron tmg/sgfr was greater than juxtamedullary nephron tmg/sgfr. Juxtamedullary nephron function was measured by puncturing loops of Henle in the exposed papillae of small rats.
Authors
Andrew D. Baines, John H. V. Bishop
Usage data is cumulative from July 2024 through July 2025.
| Usage | JCI | PMC |
|---|---|---|
| Text version | 126 | 12 |
| 47 | 10 | |
| Scanned page | 471 | 7 |
| Citation downloads | 60 | 0 |
| Totals | 704 | 29 |
| Total Views | 733 | |
Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.
Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.
Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)