Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects

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Abstract

Studies of the possibility that thyroxine (T4) is converted to 3.5,3′-triiodo-L-thyronine (T3) in the extrathyroidal tissues in man have been conducted in 13 patients, all but two of whom were athyreotic or hypothyroid, and all of whom were receiving at least physiological replacement doses of synthetic sodium-L-thyroxine.

Authors

Lewis E. Braverman, Sidney H. Ingbar, Kenneth Sterling