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The gastrointestinal stimulus to insulin release: I. Secretin
D. J. Chisholm, … , J. D. Young, L. Lazarus
D. J. Chisholm, … , J. D. Young, L. Lazarus
Published August 1, 1969
Citation Information: J Clin Invest. 1969;48(8):1453-1460. https://doi.org/10.1172/JCI106111.
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The gastrointestinal stimulus to insulin release: I. Secretin

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Abstract

The gastrointestinal stimulus to the release of insulin has been investigated in man by the use of a radioimmunoassay for secretin. Serum secretin levels rose rapidly after the oral ingestion of glucose or protein and preceded the elevation of serum insulin. An intravenous infusion of highly purified secretin caused a release of insulin when the serum secretin levels were within the physiological range.

Authors

D. J. Chisholm, J. D. Young, L. Lazarus

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