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Usage Information

Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine
Samuel Waxman, … , Jack Metz, Victor Herbert
Samuel Waxman, … , Jack Metz, Victor Herbert
Published February 1, 1969
Citation Information: J Clin Invest. 1969;48(2):284-289. https://doi.org/10.1172/JCI105984.
View: Text | PDF
Research Article

Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine

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Abstract

In B12 deficiency, inadequate DNA synthesis seems due in large measure to a block of tetrahydrofolic acid (THFA) regeneration from 5-methyl THFA (via homocysteine transmethylation).

Authors

Samuel Waxman, Jack Metz, Victor Herbert

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