Intracellular Acid-Base Regulation. I. The Response of Muscle Cells to Changes in CO₂ Tension or Extracellular Bicarbonate Concentration

^{Evans Memorial Department of Clinical Research, Massachusetts Memorial Hospitals, Boston, Mass.}

^{Department of Medicine, Boston University Medical Center, Boston, Mass.}

National Institutes of Health postdoctoral fellow, Evans Memorial Department, 1962-64.

Address requests for reprints to: Arnold S. Relman, 750 Harrison Avenue, Boston, Mass. 02118.

Submitted for publication July 20, 1964; accepted September 8, 1964.

Presented in part before the Association of American Physicians, May 1963. A preliminary report of this work has been published (1).

Supported in part by a U. S. Public Health Service research career program award (K6-AM-1589) from the National Institute of Arthritis and Metabolic Diseases, by a research grant from the National Heart Institute (HE-6395), and by a grant-in-aid from the American Heart Association.

Find articles by Adler, S. in: JCI | PubMed | Google Scholar

^{Evans Memorial Department of Clinical Research, Massachusetts Memorial Hospitals, Boston, Mass.}

^{Department of Medicine, Boston University Medical Center, Boston, Mass.}

National Institutes of Health postdoctoral fellow, Evans Memorial Department, 1962-64.

Address requests for reprints to: Arnold S. Relman, 750 Harrison Avenue, Boston, Mass. 02118.

Submitted for publication July 20, 1964; accepted September 8, 1964.

Presented in part before the Association of American Physicians, May 1963. A preliminary report of this work has been published (1).

Supported in part by a U. S. Public Health Service research career program award (K6-AM-1589) from the National Institute of Arthritis and Metabolic Diseases, by a research grant from the National Heart Institute (HE-6395), and by a grant-in-aid from the American Heart Association.

Find articles by Roy, A. in: JCI | PubMed | Google Scholar

^{Evans Memorial Department of Clinical Research, Massachusetts Memorial Hospitals, Boston, Mass.}

^{Department of Medicine, Boston University Medical Center, Boston, Mass.}

National Institutes of Health postdoctoral fellow, Evans Memorial Department, 1962-64.

Address requests for reprints to: Arnold S. Relman, 750 Harrison Avenue, Boston, Mass. 02118.

Submitted for publication July 20, 1964; accepted September 8, 1964.

Presented in part before the Association of American Physicians, May 1963. A preliminary report of this work has been published (1).

Supported in part by a U. S. Public Health Service research career program award (K6-AM-1589) from the National Institute of Arthritis and Metabolic Diseases, by a research grant from the National Heart Institute (HE-6395), and by a grant-in-aid from the American Heart Association.

Find articles by Relman, A. in: JCI | PubMed | Google Scholar