On the Concentrating Defect in Cirrhosis of the Liver

^{Clinical Pharmacology and Renal and Electrolyte Divisions of the Medical Service, Lemuel Shattuck Hospital, Department of Public Health, Commonwealth of Massachusetts, Boston, Mass.}

^{Department of Medicine, Harvard Medical School, Boston, Mass.}

^{Department of Medicine, Tufts University School of Medicine, Boston, Mass.}

This investigation was carried out during tenure as a Clinical Pharmacology Trainee and was supported by grants from the U. S. Public Health Service (H-4789, H-2324, and A-2334), and by gifts from G. D. Searle Co., Chicago, Ill.

Submitted for publication August 27, 1963; accepted October 17, 1963.

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^{Clinical Pharmacology and Renal and Electrolyte Divisions of the Medical Service, Lemuel Shattuck Hospital, Department of Public Health, Commonwealth of Massachusetts, Boston, Mass.}

^{Department of Medicine, Harvard Medical School, Boston, Mass.}

^{Department of Medicine, Tufts University School of Medicine, Boston, Mass.}

This investigation was carried out during tenure as a Clinical Pharmacology Trainee and was supported by grants from the U. S. Public Health Service (H-4789, H-2324, and A-2334), and by gifts from G. D. Searle Co., Chicago, Ill.

Submitted for publication August 27, 1963; accepted October 17, 1963.

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^{Clinical Pharmacology and Renal and Electrolyte Divisions of the Medical Service, Lemuel Shattuck Hospital, Department of Public Health, Commonwealth of Massachusetts, Boston, Mass.}

^{Department of Medicine, Harvard Medical School, Boston, Mass.}

^{Department of Medicine, Tufts University School of Medicine, Boston, Mass.}

This investigation was carried out during tenure as a Clinical Pharmacology Trainee and was supported by grants from the U. S. Public Health Service (H-4789, H-2324, and A-2334), and by gifts from G. D. Searle Co., Chicago, Ill.

Submitted for publication August 27, 1963; accepted October 17, 1963.

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^{Clinical Pharmacology and Renal and Electrolyte Divisions of the Medical Service, Lemuel Shattuck Hospital, Department of Public Health, Commonwealth of Massachusetts, Boston, Mass.}

^{Department of Medicine, Harvard Medical School, Boston, Mass.}

^{Department of Medicine, Tufts University School of Medicine, Boston, Mass.}

This investigation was carried out during tenure as a Clinical Pharmacology Trainee and was supported by grants from the U. S. Public Health Service (H-4789, H-2324, and A-2334), and by gifts from G. D. Searle Co., Chicago, Ill.

Submitted for publication August 27, 1963; accepted October 17, 1963.

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^{Clinical Pharmacology and Renal and Electrolyte Divisions of the Medical Service, Lemuel Shattuck Hospital, Department of Public Health, Commonwealth of Massachusetts, Boston, Mass.}

^{Department of Medicine, Harvard Medical School, Boston, Mass.}

^{Department of Medicine, Tufts University School of Medicine, Boston, Mass.}

This investigation was carried out during tenure as a Clinical Pharmacology Trainee and was supported by grants from the U. S. Public Health Service (H-4789, H-2324, and A-2334), and by gifts from G. D. Searle Co., Chicago, Ill.

Submitted for publication August 27, 1963; accepted October 17, 1963.

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