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Research Article Free access | 10.1172/JCI104875

STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. IV. TETRAHYDROFOLATE-DEPENDENT ENZYME SYSTEMS AND DIHYDROFOLIC REDUCTASE

J. R. Bertino, Robert Silber, M. Freeman, A. Alenty, M. Albrecht, Beverly W. Gabrio, and F. M. Huennekens

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Bertino, J. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Silber, R. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Freeman, M. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Alenty, A. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Albrecht, M. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Gabrio, B. in: PubMed | Google Scholar

Department of Biochemistry, University of Washington, and King County Central Blood Bank, Seattle, Wash.

†

Postdoctoral fellow of the National Heart Institute. Present address: Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

‡

Special fellow of the National Cancer Institute. Present address: Department of Medicine, New York University School of Medicine, New York, N. Y.

§

Present address: Division of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif.

*

This work was supported by a grant (P-203) from the American Cancer Society. Preliminary reports of this work have appeared elsewhere (1, 2).

Find articles by Huennekens, F. in: PubMed | Google Scholar

Published December 1, 1963 - More info

Published in Volume 42, Issue 12 on December 1, 1963
J Clin Invest. 1963;42(12):1899–1907. https://doi.org/10.1172/JCI104875.
© 1963 The American Society for Clinical Investigation
Published December 1, 1963 - Version history
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