Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI104696

THE DYNAMICS OF PULSUS ALTERNANS: ALTERNATING END-DIASTOLIC FIBER LENGTH AS A CAUSATIVE FACTOR

Jere H. Mitchell, Stanley J. Sarnoff, and Edmund H. Sonnenblick

Laboratory of Cardiovascular Physiology, National Heart Institute, Bethesda, Md.

*

Present Address: Established Investigator, American Heart Association, University of Texas, Southwestern Medical School, Dallas, Tex.

†

Present Address: Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, N. Y.

Find articles by Mitchell, J. in: PubMed | Google Scholar

Laboratory of Cardiovascular Physiology, National Heart Institute, Bethesda, Md.

*

Present Address: Established Investigator, American Heart Association, University of Texas, Southwestern Medical School, Dallas, Tex.

†

Present Address: Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, N. Y.

Find articles by Sarnoff, S. in: PubMed | Google Scholar

Laboratory of Cardiovascular Physiology, National Heart Institute, Bethesda, Md.

*

Present Address: Established Investigator, American Heart Association, University of Texas, Southwestern Medical School, Dallas, Tex.

†

Present Address: Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, N. Y.

Find articles by Sonnenblick, E. in: PubMed | Google Scholar

Published January 1, 1963 - More info

Published in Volume 42, Issue 1 on January 1, 1963
J Clin Invest. 1963;42(1):55–63. https://doi.org/10.1172/JCI104696.
© 1963 The American Society for Clinical Investigation
Published January 1, 1963 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 55
page 55
icon of scanned page 56
page 56
icon of scanned page 57
page 57
icon of scanned page 58
page 58
icon of scanned page 59
page 59
icon of scanned page 60
page 60
icon of scanned page 61
page 61
icon of scanned page 62
page 62
icon of scanned page 63
page 63
Version history
  • Version 1 (January 1, 1963): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts