Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI104373

COMPARISON OF EFFECTS OF PROTAMINE AND POLYBRENE, WITH SPECIAL EMPHASIS ON THE FACTOR VIII (ANTI-HEMOPHILIC GLOBULIN) DEFICIENCY INDUCED

Herbert A. Perkins, George Harkins, Frank Gerbode, Mary R. Rolfs, and D. J. Acra

Research Laboratory of the Irwin Memorial Blood Bank of the San Francisco Medical Society, San Francisco, Calif.

Surgical Research Laboratory of the Presbyterian Medical Center, San Francisco, Calif.

*

Aided by grants from the National Institutes of Health, Bethesda, Md. Abstracts of material included in this article have been previously published (1, 2).

Find articles by Perkins, H. in: PubMed | Google Scholar

Research Laboratory of the Irwin Memorial Blood Bank of the San Francisco Medical Society, San Francisco, Calif.

Surgical Research Laboratory of the Presbyterian Medical Center, San Francisco, Calif.

*

Aided by grants from the National Institutes of Health, Bethesda, Md. Abstracts of material included in this article have been previously published (1, 2).

Find articles by Harkins, G. in: PubMed | Google Scholar

Research Laboratory of the Irwin Memorial Blood Bank of the San Francisco Medical Society, San Francisco, Calif.

Surgical Research Laboratory of the Presbyterian Medical Center, San Francisco, Calif.

*

Aided by grants from the National Institutes of Health, Bethesda, Md. Abstracts of material included in this article have been previously published (1, 2).

Find articles by Gerbode, F. in: PubMed | Google Scholar

Research Laboratory of the Irwin Memorial Blood Bank of the San Francisco Medical Society, San Francisco, Calif.

Surgical Research Laboratory of the Presbyterian Medical Center, San Francisco, Calif.

*

Aided by grants from the National Institutes of Health, Bethesda, Md. Abstracts of material included in this article have been previously published (1, 2).

Find articles by Rolfs, M. in: PubMed | Google Scholar

Research Laboratory of the Irwin Memorial Blood Bank of the San Francisco Medical Society, San Francisco, Calif.

Surgical Research Laboratory of the Presbyterian Medical Center, San Francisco, Calif.

*

Aided by grants from the National Institutes of Health, Bethesda, Md. Abstracts of material included in this article have been previously published (1, 2).

Find articles by Acra, D. in: PubMed | Google Scholar

Published August 1, 1961 - More info

Published in Volume 40, Issue 8 on August 1, 1961
J Clin Invest. 1961;40(8):1421–1430. https://doi.org/10.1172/JCI104373.
© 1961 The American Society for Clinical Investigation
Published August 1, 1961 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 1421
page 1421
icon of scanned page 1422
page 1422
icon of scanned page 1423
page 1423
icon of scanned page 1424
page 1424
icon of scanned page 1425
page 1425
icon of scanned page 1426
page 1426
icon of scanned page 1427
page 1427
icon of scanned page 1428
page 1428
icon of scanned page 1429
page 1429
icon of scanned page 1430
page 1430
Version history
  • Version 1 (August 1, 1961): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts