Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI103598

STUDIES OF PULMONARY HYPERTENSION. IX. THE EFFECTS OF INTRAVENOUS HEXAMETHONIUM ON PULMONARY CIRCULATION IN PATIENTS WITH MITRAL STENOSIS

Paul N. Yu,1 R. E. Nye Jr.,1 Frank W. Lovejoy Jr.,1 Bernard F. Schreiner,1 and Bernard J. B. Yim1

Chest Laboratory of the Department of Medicine, University of Rochester School of Medicine and Dentistry, and Medical Clinics, Strong Memorial and Rochester Municipal Hospitals, Rochester, N. Y.

2

Present address: Department of Physiology, Dartmouth Medical School, Hanover, N. H.

3

Postdoctoral Research Fellow, National Heart Institute, United States Public Health Service (1956-1958).

4

Trainee, National Heart Institute, United States Public Health Service (1956-1957).

1

This study was supported in part by a grant-in-aid (H 222 C7) from the National Heart Institute of the National Institutes of Health, by a grant from the American Heart Association and New York Heart Assembly, and by the Hochstetter Fund and Ernest L. Woodward Fund.

Find articles by Yu, P. in: PubMed | Google Scholar

Chest Laboratory of the Department of Medicine, University of Rochester School of Medicine and Dentistry, and Medical Clinics, Strong Memorial and Rochester Municipal Hospitals, Rochester, N. Y.

2

Present address: Department of Physiology, Dartmouth Medical School, Hanover, N. H.

3

Postdoctoral Research Fellow, National Heart Institute, United States Public Health Service (1956-1958).

4

Trainee, National Heart Institute, United States Public Health Service (1956-1957).

1

This study was supported in part by a grant-in-aid (H 222 C7) from the National Heart Institute of the National Institutes of Health, by a grant from the American Heart Association and New York Heart Assembly, and by the Hochstetter Fund and Ernest L. Woodward Fund.

Find articles by Nye, R. in: PubMed | Google Scholar

Chest Laboratory of the Department of Medicine, University of Rochester School of Medicine and Dentistry, and Medical Clinics, Strong Memorial and Rochester Municipal Hospitals, Rochester, N. Y.

2

Present address: Department of Physiology, Dartmouth Medical School, Hanover, N. H.

3

Postdoctoral Research Fellow, National Heart Institute, United States Public Health Service (1956-1958).

4

Trainee, National Heart Institute, United States Public Health Service (1956-1957).

1

This study was supported in part by a grant-in-aid (H 222 C7) from the National Heart Institute of the National Institutes of Health, by a grant from the American Heart Association and New York Heart Assembly, and by the Hochstetter Fund and Ernest L. Woodward Fund.

Find articles by Lovejoy, F. in: PubMed | Google Scholar

Chest Laboratory of the Department of Medicine, University of Rochester School of Medicine and Dentistry, and Medical Clinics, Strong Memorial and Rochester Municipal Hospitals, Rochester, N. Y.

2

Present address: Department of Physiology, Dartmouth Medical School, Hanover, N. H.

3

Postdoctoral Research Fellow, National Heart Institute, United States Public Health Service (1956-1958).

4

Trainee, National Heart Institute, United States Public Health Service (1956-1957).

1

This study was supported in part by a grant-in-aid (H 222 C7) from the National Heart Institute of the National Institutes of Health, by a grant from the American Heart Association and New York Heart Assembly, and by the Hochstetter Fund and Ernest L. Woodward Fund.

Find articles by Schreiner, B. in: PubMed | Google Scholar

Chest Laboratory of the Department of Medicine, University of Rochester School of Medicine and Dentistry, and Medical Clinics, Strong Memorial and Rochester Municipal Hospitals, Rochester, N. Y.

2

Present address: Department of Physiology, Dartmouth Medical School, Hanover, N. H.

3

Postdoctoral Research Fellow, National Heart Institute, United States Public Health Service (1956-1958).

4

Trainee, National Heart Institute, United States Public Health Service (1956-1957).

1

This study was supported in part by a grant-in-aid (H 222 C7) from the National Heart Institute of the National Institutes of Health, by a grant from the American Heart Association and New York Heart Assembly, and by the Hochstetter Fund and Ernest L. Woodward Fund.

Find articles by Yim, B. in: PubMed | Google Scholar

Published February 1, 1958 - More info

Published in Volume 37, Issue 2 on February 1, 1958
J Clin Invest. 1958;37(2):194–201. https://doi.org/10.1172/JCI103598.
© 1958 The American Society for Clinical Investigation
Published February 1, 1958 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 194
page 194
icon of scanned page 195
page 195
icon of scanned page 196
page 196
icon of scanned page 197
page 197
icon of scanned page 198
page 198
icon of scanned page 199
page 199
icon of scanned page 200
page 200
icon of scanned page 201
page 201
Version history
  • Version 1 (February 1, 1958): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts