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Research Article Free access | 10.1172/JCI102857

THE HEMODYNAMIC EFFECTS OF HYPOTENSIVE DRUGS IN MAN. III. HEXAMETHONIUM

Edward D. Freis, John C. Rose, Edward A. Partenope, Thomas F. Higgins, Robert T. Kelley, Harold W. Schnaper, and Robert L. Johnson

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Freis, E. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Rose, J. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Partenope, E. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Higgins, T. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Kelley, R. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Schnaper, H. in: PubMed | Google Scholar

Cardiovascular Research Laboratory, Georgetown University Hospital, Washington, D. C.

Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

4

Research Fellow—Washington, D. C., Heart Association.

1

Supported in part by research grants from the National Heart Institute, U. S. Public Health Service, the Squibb Institute for Medical Research, New Brunswick, New Jersey, Irwin, Neisler and Company, Decatur, Illinois and Ciba Pharmaceuticals, Summit, New Jersey.

2

Sponsored (in part) by the VA and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

3

Hexamethonium dibromide (Bistrium) was supplied by H. Sidney Newcomer, M.D., E. R. Squibb and Sons, New York, New York.

Find articles by Johnson, R. in: PubMed | Google Scholar

Published December 1, 1953 - More info

Published in Volume 32, Issue 12 on December 1, 1953
J Clin Invest. 1953;32(12):1285–1298. https://doi.org/10.1172/JCI102857.
© 1953 The American Society for Clinical Investigation
Published December 1, 1953 - Version history
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