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Research Article Free access | 10.1172/JCI101515

CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. VIII. CLINICAL USE OF CONCENTRATED HUMAN SERUM ALBUMIN IN SHOCK, AND COMPARISON WITH WHOLE BLOOD AND WITH RAPID SALINE INFUSION

A. Cournand, R. P. Noble, E. S. Breed, H. D. Lauson, E. De F. Baldwin, G. B. Pinchot, and D. W. Richards Jr.

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Cournand, A. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Noble, R. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Breed, E. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Lauson, H. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Baldwin, E. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Pinchot, G. in: PubMed | Google Scholar

Department of Medicine, College of Physicians and Surgeons, the Tuberculosis Service, Bellevue Hospital, New York

Department of Physiology, New York University, New York

College of Medicine, New York

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University, with the collaboration of New York University. Additional support for the research was provided by the Commonwealth Fund and the Josiah Macy, Jr. Foundation.

2

The products of plasma fractionation employed in this work were developed from blood, collected by the American Red Cross, by the Department of Physical Chemistry, Harvard Medical School, Boston, Massachusetts, under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.

Find articles by Richards, D. in: PubMed | Google Scholar

Published July 1, 1944 - More info

Published in Volume 23, Issue 4 on July 1, 1944
J Clin Invest. 1944;23(4):491–505. https://doi.org/10.1172/JCI101515.
© 1944 The American Society for Clinical Investigation
Published July 1, 1944 - Version history
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