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Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?
Wilhelm Kriz, … , Brigitte Kaissling, Michel Le Hir
Wilhelm Kriz, … , Brigitte Kaissling, Michel Le Hir
Published February 1, 2011
Citation Information: J Clin Invest. 2011;121(2):468-474. https://doi.org/10.1172/JCI44595.
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Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

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Abstract

Epithelial-mesenchymal transition (EMT) has become widely accepted as a mechanism by which injured renal tubular cells transform into mesenchymal cells that contribute to the development of fibrosis in chronic renal failure. However, an increasing number of studies raise doubts about the existence of this process in vivo. Herein, we review and summarize both sides of this debate, but it is our view that unequivocal evidence supporting EMT as an in vivo process in kidney fibrosis is lacking.

Authors

Wilhelm Kriz, Brigitte Kaissling, Michel Le Hir

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Reflections on health care
Laurie H. Glimcher
Laurie H. Glimcher
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI40996.
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Reflections on health care

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Abstract

Authors

Laurie H. Glimcher

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Creating meaningful health care reform
Ralph Snyderman
Ralph Snyderman
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI41034.
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Creating meaningful health care reform

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Abstract

Authors

Ralph Snyderman

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A case for a science-informed perspective on health care reform
Paul Mischel
Paul Mischel
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI41038.
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A case for a science-informed perspective on health care reform

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Abstract

Authors

Paul Mischel

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Academic medicine and real health care reform
William N. Kelley
William N. Kelley
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI40986.
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Academic medicine and real health care reform

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Abstract

Authors

William N. Kelley

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Right to reform
Arthur L. Caplan
Arthur L. Caplan
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI40987.
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Right to reform

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Abstract

Authors

Arthur L. Caplan

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Call for a slower approach to health care reform
David G. Nathan
David G. Nathan
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI40994.
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Call for a slower approach to health care reform

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Abstract

Authors

David G. Nathan

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An academic, apolitical approach to health care reform
Robert Alpern
Robert Alpern
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI40997.
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An academic, apolitical approach to health care reform

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Abstract

Authors

Robert Alpern

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Health care reform: the differential diagnosis
Andrew R. Marks
Andrew R. Marks
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI41022.
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Health care reform: the differential diagnosis

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Abstract

Authors

Andrew R. Marks

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A view from a European medical academic who spends time in the US
Marc Feldmann
Marc Feldmann
Published September 10, 2009
Citation Information: J Clin Invest. 2009. https://doi.org/10.1172/JCI41024.
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A view from a European medical academic who spends time in the US

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Authors

Marc Feldmann

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