Review Series

Lymphocyte signal transduction

Series edited by Gary Koretzky

Activation of immune cells must be tightly controlled. Articles in the series outline our current understanding of the delicate balance of positive and negative signals implicated in T cell activation, effector function, and apoptosis, and discuss the most pressing open questions.

Articles in series

Membrane domains and the immunological synapse: keeping T cells resting and ready
Michael L. Dustin
Michael L. Dustin
Published January 15, 2002
Citation Information: J Clin Invest. 2002;109(2):155-160. https://doi.org/10.1172/JCI14842.
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ITAMs versus ITIMs: striking a balance during cell regulation
Daniel D. Billadeau, Paul J. Leibson
Daniel D. Billadeau, Paul J. Leibson
Published January 15, 2002
Citation Information: J Clin Invest. 2002;109(2):161-168. https://doi.org/10.1172/JCI14843.
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ITAMs versus ITIMs: striking a balance during cell regulation

Abstract

Authors

Daniel D. Billadeau, Paul J. Leibson

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Activation and inhibition of lymphocytes by costimulation
Kenneth A. Frauwirth, Craig B. Thompson
Kenneth A. Frauwirth, Craig B. Thompson
Published February 1, 2002
Citation Information: J Clin Invest. 2002;109(3):295-299. https://doi.org/10.1172/JCI14941.
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Activation and inhibition of lymphocytes by costimulation

Abstract

Authors

Kenneth A. Frauwirth, Craig B. Thompson

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Adapters in lymphocyte signaling
Albrecht Leo, … , Vaclav Horejsi, Burkhart Schraven
Albrecht Leo, … , Vaclav Horejsi, Burkhart Schraven
Published February 1, 2002
Citation Information: J Clin Invest. 2002;109(3):301-309. https://doi.org/10.1172/JCI14942.
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Adapters in lymphocyte signaling

Abstract

Authors

Albrecht Leo, Jürgen Wienands, Gottfried Baier, Vaclav Horejsi, Burkhart Schraven

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T helper subset development: roles of instruction, selection, and transcription
J. David Farrar, … , Helene Asnagli, Kenneth M. Murphy
J. David Farrar, … , Helene Asnagli, Kenneth M. Murphy
Published February 15, 2002
Citation Information: J Clin Invest. 2002;109(4):431-435. https://doi.org/10.1172/JCI15093.
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T helper subset development: roles of instruction, selection, and transcription

Abstract

Authors

J. David Farrar, Helene Asnagli, Kenneth M. Murphy

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Death receptors couple to both cell proliferation and apoptosis
Ralph C. Budd
Ralph C. Budd
Published February 15, 2002
Citation Information: J Clin Invest. 2002;109(4):437-442. https://doi.org/10.1172/JCI15077.
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Series Introduction: Stimulation and inhibition of immune responses: an intricate balancing act
Gary Koretzky
Gary Koretzky
Published January 1, 2002
Citation Information: J Clin Invest. 2002;109(1):7-8. https://doi.org/10.1172/JCI14820.
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Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases
Michelle L. Hermiston, … , Ravindra Majeti, Arthur Weiss
Michelle L. Hermiston, … , Ravindra Majeti, Arthur Weiss
Published January 1, 2002
Citation Information: J Clin Invest. 2002;109(1):9-14. https://doi.org/10.1172/JCI14794.
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Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases

Abstract

Authors

Michelle L. Hermiston, Zheng Xu, Ravindra Majeti, Arthur Weiss

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