Activation of immune cells must be tightly controlled. Articles in the series outline our current understanding of the delicate balance of positive and negative signals implicated in T cell activation, effector function, and apoptosis, and discuss the most pressing open questions.
Michael L. Dustin
Daniel D. Billadeau, Paul J. Leibson
Kenneth A. Frauwirth, Craig B. Thompson
Albrecht Leo, Jürgen Wienands, Gottfried Baier, Vaclav Horejsi, Burkhart Schraven
J. David Farrar, Helene Asnagli, Kenneth M. Murphy
Ralph C. Budd
Michelle L. Hermiston, Zheng Xu, Ravindra Majeti, Arthur Weiss