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Abstract
JC virus (JCV) causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease in humans. The disease, once considered fatal, is now managed with immune reconstitution therapy; however, surviving patients remain severely debilitated. Until now, there has been no animal model to study JCV in the brain, and research into treatment has relied on cell culture systems. In this issue of the
Authors
Sheila A. Haley, Walter J. Atwood
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ISSN: 0021-9738 (print), 1558-8238 (online)