Although the cognitive and biological characteristics of Alzheimer’s disease (AD) are well known and mouse models of AD are available, current treatments for AD-related cognitive deficits have quite limited efficacy. The development of tasks with cross-species validity may enable better prediction of the efficacy of potential new treatments. In this issue of the
Kerin K. Higa, Jared W. Young, Mark A. Geyer
Schematic of hidden target learning arenas for mouse and human tasks.