Left ventricular hypertrophy is an initial compensatory mechanism in response to cardiac stress that can degenerate into heart failure and sudden cardiac death. Recent studies have shown that microRNAs (miRs) regulate several aspects of cardiovascular diseases. In this issue of the
Ciro Indolfi, Antonio Curcio
Dynamics of fibroblast-mediated exosome secretion and pivotal miRs involved in cardiac hypertrophy.