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Usage Information

Oxidative stress and intracellular infections: more iron to the fire
Norma W. Andrews
Norma W. Andrews
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Commentary

Oxidative stress and intracellular infections: more iron to the fire

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Abstract

The immune system’s battle against pathogens includes the “respiratory burst,” a rapid release of ROS from leukocytes, thought to play a role in destroying the invading species. In this issue of the JCI, Paiva et al. demonstrate that oxidative stress actually enhances infection with the protozoan Trypanosoma cruzi, by a mechanism that may involve facilitating parasite access to iron. Their findings suggest a novel direction for the development of drugs against intracellular parasites.

Authors

Norma W. Andrews

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Usage data is cumulative from February 2025 through February 2026.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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