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The innate immune system in cystic fibrosis lung disease
Robert Bals, … , Daniel J. Weiner, James M. Wilson
Robert Bals, … , Daniel J. Weiner, James M. Wilson
Published February 1, 1999
Citation Information: J Clin Invest. 1999;103(3):303-307. https://doi.org/10.1172/JCI6277.
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Perspective

The innate immune system in cystic fibrosis lung disease

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Abstract

Authors

Robert Bals, Daniel J. Weiner, James M. Wilson

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Figure 1

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Host defense mechanisms of the respiratory epithelium. Cough and cilia m...
Host defense mechanisms of the respiratory epithelium. Cough and cilia mechanically remove inhaled debris and microorganisms entrapped in mucus, a mechanism called mucociliary clearance. Multiple substances with pro- and antiinflammatory as well as antimicrobial activities are secreted by epithelial cells and function as an innate immune barrier. Macrophages, B and T lymphocytes, neutrophils and also epithelial cells represent cellular components of the innate and adaptive immune systems.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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