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Usage Information

A look at autoimmunity and inflammation in the eye
Rachel R. Caspi
Rachel R. Caspi
Published September 1, 2010
Citation Information: J Clin Invest. 2010;120(9):3073-3083. https://doi.org/10.1172/JCI42440.
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Review

A look at autoimmunity and inflammation in the eye

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Abstract

Autoimmune and inflammatory uveitis are a group of potentially blinding intraocular inflammatory diseases that arise without a known infectious trigger and are often associated with immunological responses to unique retinal proteins. In the United States, about 10% of the cases of severe visual handicap are attributed to this group of disorders. As I discuss here, experimental models of ocular autoimmunity targeting retinal proteins have brought about a better understanding of the basic immunological mechanisms involved in the pathogenesis of uveitis and are serving as templates for the development of novel therapies.

Authors

Rachel R. Caspi

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Usage data is cumulative from April 2020 through April 2021.

Usage JCI PMC
Text version 1,090 1,019
PDF 170 1,167
Figure 219 0
Table 127 0
Supplemental data 0 28
Citation downloads 25 0
Totals 1,631 2,214
Total Views 3,845
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