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Usage Information

Trafficking of immune cells in the central nervous system
Emma H. Wilson, Wolfgang Weninger, Christopher A. Hunter
Emma H. Wilson, Wolfgang Weninger, Christopher A. Hunter
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Science in Medicine

Trafficking of immune cells in the central nervous system

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Abstract

The CNS is an immune-privileged environment, yet the local control of multiple pathogens is dependent on the ability of immune cells to access and operate within this site. However, inflammation of the distinct anatomical sites (i.e., meninges, cerebrospinal fluid, and parenchyma) associated with the CNS can also be deleterious. Therefore, control of lymphocyte entry and migration within the brain is vital to regulate protective and pathological responses. In this review, several recent advances are highlighted that provide new insights into the processes that regulate leukocyte access to, and movement within, the brain.

Authors

Emma H. Wilson, Wolfgang Weninger, Christopher A. Hunter

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Usage data is cumulative from May 2025 through May 2026.

Usage JCI PMC
Text version 2,206 252
PDF 201 42
Figure 483 0
Table 177 0
Citation downloads 115 0
Totals 3,182 294
Total Views 3,476
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ISSN: 0021-9738 (print), 1558-8238 (online)

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