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Usage Information

Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis
Joel D. Ernst, Giraldina Trevejo-Nuñez, Niaz Banaiee
Joel D. Ernst, Giraldina Trevejo-Nuñez, Niaz Banaiee
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Science in Medicine

Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis

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Abstract

Tuberculosis kills nearly 2 million people annually, and current approaches to tuberculosis control are expensive, have limited efficacy, and are vulnerable to being overcome by extensively drug-resistant strains of Mycobacterium tuberculosis. Determination of the genome sequence of M. tuberculosis has revolutionized tuberculosis research, contributed to major advances in the understanding of the evolution and pathogenesis of M. tuberculosis, and facilitated development of new diagnostic tests with increased specificity for tuberculosis. In this review, we describe some of the major progress in tuberculosis research that has resulted from knowledge of the genome sequence and note some of the problems that remain unsolved.

Authors

Joel D. Ernst, Giraldina Trevejo-Nuñez, Niaz Banaiee

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Usage data is cumulative from August 2025 through August 2026.

Usage JCI PMC
Text version 939 80
PDF 308 21
Figure 370 2
Citation downloads 205 0
Totals 1,822 103
Total Views 1,925
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

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