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Usage Information

Drug discovery in jeopardy
Pedro Cuatrecasas
Pedro Cuatrecasas
Published November 1, 2006
Citation Information: J Clin Invest. 2006;116(11):2837-2842. https://doi.org/10.1172/JCI29999.
View: Text | PDF
Science and Society

Drug discovery in jeopardy

  • Text
  • PDF
Abstract

Despite striking advances in the biomedical sciences, the flow of new drugs has slowed to a trickle, impairing therapeutic advances as well as the commercial success of drug companies. Reduced productivity in the drug industry is caused mainly by corporate policies that discourage innovation. This is compounded by various consequences of mega-mergers, the obsession for blockbuster drugs, the shift of control of research from scientists to marketers, the need for fast sales growth, and the discontinuation of development compounds for nontechnical reasons. Lessons from the past indicate that these problems can be overcome, and herein, new and improved directions for drug discovery are suggested.

Authors

Pedro Cuatrecasas

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Usage data is cumulative from July 2024 through July 2025.

Usage JCI PMC
Text version 1,010 46
PDF 125 28
Citation downloads 118 0
Totals 1,253 74
Total Views 1,327
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