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Usage Information

The application of biofilm science to the study and control of chronic bacterial infections
William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, Garth Ehrlich
William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, Garth Ehrlich
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Perspective Series

The application of biofilm science to the study and control of chronic bacterial infections

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Abstract

Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.

Authors

William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, Garth Ehrlich

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Usage data is cumulative from April 2025 through April 2026.

Usage JCI PMC
Text version 3,030 157
PDF 430 50
Figure 818 18
Citation downloads 165 0
Totals 4,443 225
Total Views 4,668
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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