Generic brain-activation maps in response to a PL task. (a) In healthy subjects, regions of activation are demonstrated in the striatum, thalamus, cingulate gyrus, insula, and cerebellum. (b) In patients with schizophrenia, there is a lack of activation in these same regions. Below each image, z coordinates are shown, left to right. Reproduced with permission from Schizophrenia Research (84).