Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Insights and treatment options for psychiatric disorders guided by functional MRI
Tonmoy Sharma
Tonmoy Sharma
Published July 1, 2003
Citation Information: J Clin Invest. 2003;112(1):10-18. https://doi.org/10.1172/JCI19166.
View: Text | PDF
Perspective

Insights and treatment options for psychiatric disorders guided by functional MRI

  • Text
  • PDF
Abstract

Authors

Tonmoy Sharma

×

Figure 3

Options: View larger image (or click on image) Download as PowerPoint
An illustration of pattern-trial rules used in a PL test. The asterisk-l...
An illustration of pattern-trial rules used in a PL test. The asterisk-like target moves among four locations on the screen, which is divided into four equal quadrants by two intersecting white lines. The movement of the target during the pattern-trial test is predictable in 75% of cases, as determined by three specific rules: (a) a horizontal target movement is followed by a vertical target movement, (b) a vertical target movement is followed by a diagonal target movement, and (c) a diagonal target movement is followed by a horizontal movement. The fourth movement of the target during the pattern trials is unpredictable. In the control state, individuals are subjected to only random target movements. During the experimental test, individuals are subjected to blocks of patterns and required to determine the expected projectory of imminent movement, and their subsequent reaction time is recorded. Reproduced with permission from Schizophrenia Research (84).

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts