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Series Introduction: The immuno-neuroendocrine interface
Shlomo Melmed
Shlomo Melmed
Published December 1, 2001
Citation Information: J Clin Invest. 2001;108(11):1563-1566. https://doi.org/10.1172/JCI14604.
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Series Introduction: The immuno-neuroendocrine interface

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Authors

Shlomo Melmed

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Figure 1

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Model for regulation of anterior pituitary hormone secretion by three ti...
Model for regulation of anterior pituitary hormone secretion by three tiers of control. Hypothalamic hormones traverse the portal system and impinge directly upon their respective target cells. Intrapituitary cytokines and growth factors regulate tropic cell function by paracrine (and autocrine) control. Peripheral hormones exert negative feedback inhibition of respective pituitary trophic hormone synthesis and secretion. Reproduced with permission from Endocrine Reviews (2).

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