Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated
Simon J. Atkinson
Department of Biology, Indiana University – Purdue University Indianapolis, Indianapolis, Indiana, USA.
Address correspondence to: Simon J. Atkinson, 755 W. Michigan Street, UL-1140, Indianapolis Indiana 46202, USA. Phone: 317.274.1020; Email: satkinso@iupui.edu.
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First published June 4, 2018 - More info
J Clin Invest. 2018;128(7):2754–2756. https://doi.org/10.1172/JCI121741.
Copyright © 2018, American Society for Clinical Investigation
Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging. In the current issue of the JCI, Lau et al. use a mouse model of CI-AKI to study the role of resident and infiltrating phagocytes, recruited leukocytes, and tubular cells in the immune surveillance response to contrast agents. This study has the potential to provide innovative therapies for human CI-AKI.
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Copyright © 2018 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)