Citations to this article

Metabolism of steroid and amino acid moieties of conjugated bile acids in man: II. Glycine-conjugated dihydroxy bile acids
Gershon W. Hepner, … , Alan F. Hofmann, Paul J. Thomas
Gershon W. Hepner, … , Alan F. Hofmann, Paul J. Thomas
Published July 1, 1972
Citation Information: J Clin Invest. 1972;51(7):1898-1905. https://doi.org/10.1172/JCI106992.
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Metabolism of steroid and amino acid moieties of conjugated bile acids in man: II. Glycine-conjugated dihydroxy bile acids

Abstract

Chenodeoxycholyl-2,4-3H-glycine-1-14C and deoxycholyl-2,4-3H-glycine-1-14C were synthesized and administered orally to 10 healthy subjects. Distribution of radioactivity among bile acids and specific activity of steroid and amino acid moieties were determined in bile samples. 3H and 14C were measured in feces. 14C in breath was calculated from interval 14CO2 specific activity determinations.

Authors

Gershon W. Hepner, Alan F. Hofmann, Paul J. Thomas

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