Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
K Horie, T Miyata, K Maeda, S Miyata, S Sugiyama, H Sakai, C van Ypersole de Strihou, V M Monnier, J L Witztum, K Kurokawa
The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.
P A Rufo, D Merlin, M Riegler, M H Ferguson-Maltzman, B L Dickinson, C Brugnara, S L Alper, W I Lencer
Interferon-gamma and tumor necrosis factor-alpha specifically induce formation of cytomegalovirus-permissive monocyte-derived macrophages that are refractory to the antiviral activity of these cytokines.
Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.