Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Issue published November 15, 1997 Previous issue | Next issue

  • Volume 100, Issue 10
Go to section:
  • Corrections
  • Perspectives
  • Research Articles
Corrections
Correction
/articles/view/119735C1
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2637-2637. https://doi.org/10.1172/JCI119735C1.
View: Text | PDF | Amended Article

Correction

  • Text
  • PDF
Abstract

Authors

×

Correction
/articles/view/119748E1
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2639-2639. https://doi.org/10.1172/JCI119748E1.
View: Text | PDF | Amended Article

Correction

  • Text
  • PDF
Abstract

Authors

×
Perspectives
Inducible nitric oxide synthase: what difference does it make?
C Nathan
C Nathan
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2417-2423. https://doi.org/10.1172/JCI119782.
View: Text | PDF

Inducible nitric oxide synthase: what difference does it make?

  • Text
  • PDF
Abstract

Perspective

Authors

C Nathan

×

Nitric oxide in excitable tissues: physiological roles and disease.
K S Christopherson, D S Bredt
K S Christopherson, D S Bredt
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2424-2429. https://doi.org/10.1172/JCI119783.
View: Text | PDF

Nitric oxide in excitable tissues: physiological roles and disease.

  • Text
  • PDF
Abstract

Perspective

Authors

K S Christopherson, D S Bredt

×
Research Articles
Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.
U Mayer, … , P Borst, A H Schinkel
U Mayer, … , P Borst, A H Schinkel
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2430-2436. https://doi.org/10.1172/JCI119784.
View: Text | PDF

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.

  • Text
  • PDF
Abstract

Research Article

Authors

U Mayer, E Wagenaar, B Dorobek, J H Beijnen, P Borst, A H Schinkel

×

Vasopressin potentiates mineralocorticoid selectivity by stimulating 11 beta hydroxysteroid deshydrogenase in rat collecting duct.
N Alfaidy, … , J P Bonvalet, N Farman
N Alfaidy, … , J P Bonvalet, N Farman
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2437-2442. https://doi.org/10.1172/JCI119785.
View: Text | PDF

Vasopressin potentiates mineralocorticoid selectivity by stimulating 11 beta hydroxysteroid deshydrogenase in rat collecting duct.

  • Text
  • PDF
Abstract

Research Article

Authors

N Alfaidy, M Blot-Chabaud, J P Bonvalet, N Farman

×

In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.
A B Lentsch, … , V Sarma, P A Ward
A B Lentsch, … , V Sarma, P A Ward
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2443-2448. https://doi.org/10.1172/JCI119786.
View: Text | PDF

In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.

  • Text
  • PDF
Abstract

Research Article

Authors

A B Lentsch, T P Shanley, V Sarma, P A Ward

×

Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection.
A Räisänen-Sokolowski, … , A Satoskar, M E Russell
A Räisänen-Sokolowski, … , A Satoskar, M E Russell
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2449-2456. https://doi.org/10.1172/JCI119787.
View: Text | PDF

Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection.

  • Text
  • PDF
Abstract

Research Article

Authors

A Räisänen-Sokolowski, P L Mottram, T Glysing-Jensen, A Satoskar, M E Russell

×

In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.
R C Rubenstein, … , M E Egan, P L Zeitlin
R C Rubenstein, … , M E Egan, P L Zeitlin
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2457-2465. https://doi.org/10.1172/JCI119788.
View: Text | PDF

In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.

  • Text
  • PDF
Abstract

Research Article

Authors

R C Rubenstein, M E Egan, P L Zeitlin

×

Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.
R Sehmi, … , P M O'Byrne, J A Denburg
R Sehmi, … , P M O'Byrne, J A Denburg
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2466-2475. https://doi.org/10.1172/JCI119789.
View: Text | PDF

Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.

  • Text
  • PDF
Abstract

Research Article

Authors

R Sehmi, L J Wood, R Watson, R Foley, Q Hamid, P M O'Byrne, J A Denburg

×

Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts.
K L Insogna, … , J B Levy, R Baron
K L Insogna, … , J B Levy, R Baron
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2476-2485. https://doi.org/10.1172/JCI119790.
View: Text | PDF

Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts.

  • Text
  • PDF
Abstract

Research Article

Authors

K L Insogna, M Sahni, A B Grey, S Tanaka, W C Horne, L Neff, M Mitnick, J B Levy, R Baron

×

Spatiotemporal complexity of ventricular fibrillation revealed by tissue mass reduction in isolated swine right ventricle. Further evidence for the quasiperiodic route to chaos hypothesis.
Y H Kim, … , H S Karagueuzian, P S Chen
Y H Kim, … , H S Karagueuzian, P S Chen
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2486-2500. https://doi.org/10.1172/JCI119791.
View: Text | PDF

Spatiotemporal complexity of ventricular fibrillation revealed by tissue mass reduction in isolated swine right ventricle. Further evidence for the quasiperiodic route to chaos hypothesis.

  • Text
  • PDF
Abstract

Research Article

Authors

Y H Kim, A Garfinkel, T Ikeda, T J Wu, C A Athill, J N Weiss, H S Karagueuzian, P S Chen

×

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes.
P Ray, … , R A Flavell, J A Elias
P Ray, … , R A Flavell, J A Elias
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2501-2511. https://doi.org/10.1172/JCI119792.
View: Text | PDF

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes.

  • Text
  • PDF
Abstract

Research Article

Authors

P Ray, W Tang, P Wang, R Homer, C Kuhn 3rd, R A Flavell, J A Elias

×

Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist.
J W Pippin, … , L Meijer, S J Shankland
J W Pippin, … , L Meijer, S J Shankland
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2512-2520. https://doi.org/10.1172/JCI119793.
View: Text | PDF

Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist.

  • Text
  • PDF
Abstract

Research Article

Authors

J W Pippin, Q Qu, L Meijer, S J Shankland

×

Intercellular adhesion molecule-1 and CD36 synergize to mediate adherence of Plasmodium falciparum-infected erythrocytes to cultured human microvascular endothelial cells.
C J McCormick, … , C I Newbold, A R Berendt
C J McCormick, … , C I Newbold, A R Berendt
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2521-2529. https://doi.org/10.1172/JCI119794.
View: Text | PDF

Intercellular adhesion molecule-1 and CD36 synergize to mediate adherence of Plasmodium falciparum-infected erythrocytes to cultured human microvascular endothelial cells.

  • Text
  • PDF
Abstract

Research Article

Authors

C J McCormick, A Craig, D Roberts, C I Newbold, A R Berendt

×

Constitutive activation of the gastrin-releasing peptide receptor expressed by the nonmalignant human colon epithelial cell line NCM460.
H A Ferris, … , M M Rasenick, R V Benya
H A Ferris, … , M M Rasenick, R V Benya
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2530-2537. https://doi.org/10.1172/JCI119795.
View: Text | PDF

Constitutive activation of the gastrin-releasing peptide receptor expressed by the nonmalignant human colon epithelial cell line NCM460.

  • Text
  • PDF
Abstract

Research Article

Authors

H A Ferris, R E Carroll, M M Rasenick, R V Benya

×

Lupus-specific antibodies reveal an altered pattern of somatic mutation.
A J Manheimer-Lory, … , C Aranow, B Diamond
A J Manheimer-Lory, … , C Aranow, B Diamond
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2538-2546. https://doi.org/10.1172/JCI119796.
View: Text | PDF

Lupus-specific antibodies reveal an altered pattern of somatic mutation.

  • Text
  • PDF
Abstract

Research Article

Authors

A J Manheimer-Lory, G Zandman-Goddard, A Davidson, C Aranow, B Diamond

×

Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.
J Westerlund, … , E Gylfe, P Bergsten
J Westerlund, … , E Gylfe, P Bergsten
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2547-2551. https://doi.org/10.1172/JCI119797.
View: Text | PDF

Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.

  • Text
  • PDF
Abstract

Research Article

Authors

J Westerlund, E Gylfe, P Bergsten

×

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
L Boring, … , H E Broxmeyer, I F Charo
L Boring, … , H E Broxmeyer, I F Charo
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2552-2561. https://doi.org/10.1172/JCI119798.
View: Text | PDF

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

  • Text
  • PDF
Abstract

Research Article

Authors

L Boring, J Gosling, S W Chensue, S L Kunkel, R V Farese Jr, H E Broxmeyer, I F Charo

×

Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy.
A R Crawford, … , P Borst, J M Crawford
A R Crawford, … , P Borst, J M Crawford
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2562-2567. https://doi.org/10.1172/JCI119799.
View: Text | PDF

Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy.

  • Text
  • PDF
Abstract

Research Article

Authors

A R Crawford, A J Smith, V C Hatch, R P Oude Elferink, P Borst, J M Crawford

×

Mutant endoglin in hereditary hemorrhagic telangiectasia type 1 is transiently expressed intracellularly and is not a dominant negative.
N Pece, … , J L Wrana, M Letarte
N Pece, … , J L Wrana, M Letarte
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2568-2579. https://doi.org/10.1172/JCI119800.
View: Text | PDF

Mutant endoglin in hereditary hemorrhagic telangiectasia type 1 is transiently expressed intracellularly and is not a dominant negative.

  • Text
  • PDF
Abstract

Research Article

Authors

N Pece, S Vera, U Cymerman, R I White Jr, J L Wrana, M Letarte

×

Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.
G A Soff, … , S Gately, T M Lincoln
G A Soff, … , S Gately, T M Lincoln
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2580-2587. https://doi.org/10.1172/JCI119801.
View: Text | PDF

Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.

  • Text
  • PDF
Abstract

Research Article

Authors

G A Soff, T L Cornwell, D L Cundiff, S Gately, T M Lincoln

×

Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects.
M R Knowles, … , J T Gatzy, R C Boucher
M R Knowles, … , J T Gatzy, R C Boucher
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2588-2595. https://doi.org/10.1172/JCI119802.
View: Text | PDF | Correction

Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects.

  • Text
  • PDF
Abstract

Research Article

Authors

M R Knowles, J M Robinson, R E Wood, C A Pue, W M Mentz, G C Wager, J T Gatzy, R C Boucher

×

Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.
Y Imai, … , C Rees, D R Clemmons
Y Imai, … , C Rees, D R Clemmons
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2596-2605. https://doi.org/10.1172/JCI119803.
View: Text | PDF

Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.

  • Text
  • PDF
Abstract

Research Article

Authors

Y Imai, W H Busby Jr, C E Smith, J B Clarke, A J Garmong, G D Horwitz, C Rees, D R Clemmons

×

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.
D H Kedes, … , R Renne, D Ganem
D H Kedes, … , R Renne, D Ganem
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2606-2610. https://doi.org/10.1172/JCI119804.
View: Text | PDF

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.

  • Text
  • PDF
Abstract

Research Article

Authors

D H Kedes, M Lagunoff, R Renne, D Ganem

×

Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype.
S D Rybalkin, … , E G Krebs, J A Beavo
S D Rybalkin, … , E G Krebs, J A Beavo
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2611-2621. https://doi.org/10.1172/JCI119805.
View: Text | PDF

Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype.

  • Text
  • PDF
Abstract

Research Article

Authors

S D Rybalkin, K E Bornfeldt, W K Sonnenburg, I G Rybalkina, K S Kwak, K Hanson, E G Krebs, J A Beavo

×

Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand.
L Georgescu, … , K B Elkon, M K Crow
L Georgescu, … , K B Elkon, M K Crow
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2622-2633. https://doi.org/10.1172/JCI119806.
View: Text | PDF

Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand.

  • Text
  • PDF
Abstract

Research Article

Authors

L Georgescu, R K Vakkalanka, K B Elkon, M K Crow

×
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts