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R
esearch into the pathogenesis, prevention, and control of infectious and parasitic
diseases remains a global priority, as these scourges continue to be a substantial
cause of mortality and morbidity. The plethora of molecular tools that are now
readily available has facilitated a genome-wide approach to studying the pathogenesis
of such diseases, with direct implications for disease prevention and treatment. The
articles in this Review Series describe how genome-wide approaches have provided
insight into a range of human pathogens, leading to greater understanding of the
human diseases that they cause, and highlight some of the challenges that must be
overcome if we are to maximize what we learn from the wealth of genomic information
now available.
