Binding of Chemotactic Collagen-Derived Peptides to Fibroblasts: THE RELATIONSHIP TO FIBROBLAST CHEMOTAXIS

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Abstract

We previously showed that collagen, α-chains, and collagen-derived peptide fragments induce chemotactic migration of human fibroblasts in vitro. We now describe biochemical and immunological evidence showing there are binding sites for collagen peptides on fibroblast membranes.

Authors

Thomas M. Chiang, Arnold E. Postlethwaite, Edwin H. Beachey, Jerome M. Seyer, Andrew H. Kang