Age-dependent incidence, time course, and consequences of thymic renewal in adults
J. Clin. Invest. Frances T. Hakim, et al. 115:930 doi:10.1172/JCI22492 [Go to this article.]

Figure 2
Effect of age on recovery of thymic size after APBSCT. (A) Spearman nonparametric correlation demonstrates that the maximum TI achieved in the first 2 years after transplant (as assessed in Figure 1) is dependent on age at time of treatment. (B) Time course of thymic enlargement as stratified by age. Each line represents the individual time course during the first 2 years after transplant of changes in TI of a patient who achieved a maximum TI of 2, the size of a normal adult thymus. The number of patients in each age range and the incidence of those individuals with thymic enlargement (4 of 5, TI ≥ 2) is in parentheses above each graph. The gray bands represent the range of minimal thymic size observed after transplant in patients demonstrating no significant change, whose time courses would otherwise overlap.