Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
J. Clin. Invest. S. Eddahibi, et al. 105:1555 doi:10.1172/JCI8678 [Go to this article.]

Figure 3
RVSP (a) and right ventricle/left ventricle plus septum weight (RV/LV+S) (b) in 5-HTT^+/+ and 5-HTT^–/– mutant mice exposed to normoxia (N) (n = 9 in each genotype) or 10% O₂ for 2 weeks (H-2 weeks) (n = 9 of each genotype) or 5 weeks (H-5 weeks) (n = 8 of each genotype). ^AP < 0.05, ^BP < 0.01, and ^CP < 0.001 as compared with corresponding values in 5-HTT^+/+ mice under similar conditions.