Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
J. Clin. Invest. Peter Garred, et al. 104:431 doi:10.1172/JCI6861 [Go to this article.]

Figure 2
The lung function (FVC and FEV1, expressed as percentages) measured from 1989 to 1997 was stratified according to A/A (n = 96) and the X/Y promoter (base substitution in position –221) on the functional A chromosome in structural MBL allele heterozygotes (YA/0, n = 34; and XA/0, n = 15) and those with homozygous defect (0/0, n = 4). The numbers refer to those included in the study in 1989. Mean is indicated. The general improvement in lung function data from 1995 to 1997 probably is due to a combination of the change in analyzing equipment, the number of dropouts, and improved treatment.