Prenatal nicotine increases pulmonary α7 nicotinic receptor expression and alters fetal lung development in monkeys
J. Clin. Invest. Harmanjatinder S. Sekhon, et al. 103:637 doi:10.1172/JCI5232 [
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Figure 1Effect of prenatal exposure to nicotine on lung structure. Hematoxylin-stained sections from control (
a) and nicotine-treated (
b) 134-day fetal monkey lungs. The left lung with intact trachea was fixed with 10% buffered formaldehyde at 20 cm constant transpulmonary water pressure for 72 h. Midsagittal blocks were cut, embedded in paraffin, and 5-μm sections cut. ×400.