Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression
J. Clin. Invest. Jean-Eric Ghia, et al. 118:2209 doi:10.1172/JCI32849 [
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Figure 7Effect of VXP on DMI treatment of colitis. (
A) Influence of 12 days of DMI (15 mg/d, i.p.) treatment, starting 2 days after the beginning of reserpine (1 μg/d) treatment and/or VXP treatment on behavior. DMI effect was not affected by VXP. (
B) Macroscopic score, (
C) MPO activity, and (
D) acetylcholine levels in colonic tissue after 5 days of DSS 5% regime. *
P < 0.05. The values are shown as means ± SEM.
