Ablation of Cbl-b provides protection against transplanted and spontaneous tumors
J. Clin. Invest. Jeffrey Y. Chiang, et al. 117:1029 doi:10.1172/JCI29472 [Go to this article.]

Figure 4
Tumor incidence in Cblb^–/–ATM^–/– double-mutant mice. Numbers of surviving ATM^–/– single-mutant (including 5 ATM^–/–Cblb^+/+ and 18 ATM^–/–Cblb^+/–) and Cblb^–/–ATM^–/– (n = 21) mice are shown. Cblb^–/–ATM^–/– double-mutant mice exhibited reduced incidence and delayed onset of spontaneous lymphoma.