Mutation of β-glucosidase 2 causes glycolipid storage disease and impaired male fertility
J. Clin. Invest. Yildiz Yildiz, et al. 116:2985 doi:10.1172/JCI29224 [Go to this article.]

Figure 4
Failure of sperm from Gba2^–/– mice to bind the zona pellucida. Cumulus enclosed oocytes from Gba2^+/+ mice were incubated for 5 hours with either Gba2^+/+ sperm (left panel) or Gba2^–/– sperm (right panel) and then examined by light microscopy. Sperm from knockout mice were deficient in zona pellucida binding. Original magnification, ×160.