Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance
of Bordetella pertussis
J. Clin. Invest. Girish S. Kirimanjeswara, et al. 115:3594 doi:10.1172/JCI24609 [
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Figure 1Serum antibodies clear
B. pertussis after 7 days of inoculation. C57BL/6 mice were inoculated with 5 × 10
5 CFU of
B. pertussis and adoptively transferred with 200 μl of naive serum (circles) or convalescent-phase serum (triangles). Lungs were harvested on the indicated days, and bacterial numbers were enumerated and expressed as geometric mean ± SEM. Dotted line denotes limit of detection.
n = 4 per group. *
P < 0.001.
