Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS
J. Clin. Invest. Luisa M. Villar, et al. 115:187 doi:10.1172/JCI22833 [Go to this article.]

Figure 7
Evaluation of disease course. The number of relapses during follow-up (A) and the neurological disability at the end of the study (B) were monitored in patients with and without LS-OCMBs. Comparisons were made by a Mann-Whitney U test. Patients with LS-OCMBs had more relapses (P = 0.0004) and became more disabled (P = 0.02) than those without LS-OCMBs.