Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model
J. Clin. Invest. Yasushi Takagi, et al. 115:102 doi:10.1172/JCI21137 [
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Figure 5Survival of ES cell–derived DA neurons in the striatum. (
A–
C) Grafted cells (BrdU-labeled, green) survived and differentiated into DA neurons (TH-positive, red) along the needle tract (merged image
C). Scale bar: 500 μm. (
D–
I) Colocalization (arrows in
F and
I) of BrdU (
D,
F,
G, and
I, green) and TH (
E and
F, red) or DAT (
H and
I, red) shows that graft-derived cells have dopaminergic character. Scale bar: 50 μm.
