Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model
J. Clin. Invest. Yasushi Takagi, et al. 115:102 doi:10.1172/JCI21137 [
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Figure 4Function of ES cell–derived neurospheres in MPTP-treated monkeys. Behavioral scores (
A) and PET study (
B and
C) of ES cell–transplanted (
n = 6) and sham-operated animals (
n = 4). (
B) Mean Ki values from entire putamen. (
C) Increased
18F-fluorodopa uptake in the putamen of ES cell–transplanted animals. All values are mean ± SD. *
P < 0.05.