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Quorum sensing and biofilm formation in Streptococcal infections
Dennis G. Cvitkovitch, Yung-Hua Li, Richard P. Ellen
Published in Volume 112, Issue 11
J Clin Invest. 2003; 112(11):1626–1632 doi:10.1172/JCI20430
This article Copyright © 2003, The American Society for Clinical Investigation
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Figure 3

Scanning confocal laser microscope images of 16 h S. mutans biofilms. Panels a–c show the X-Y planes (top view), while the panels d–f show the X-Z planes (side view). The panels illustrate (a, d) a normal biofilm formed by the parent strain NG8 and (b, e) an aberrant biofilm formed by the comC– mutant defective in making a CSP. The wild-type appearance of the biofilm is restored by addition of synthetic CSP (c, f). Reproduced with permission from The Journal of Bacteriology (12).

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