Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia
J. Clin. Invest. Konrad Talbot, et al. 113:1353 doi:10.1172/JCI20425 [
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Figure 2Tests of dysbindin-1 antibody specificity in COS-7 cells. Such cells normally express no detectable dysbindin. (
A) The antibody PA3111Ae2 (1:100) recognizes dysbindin-1 only in COS-7 cells transfected with dysbindin-1 expression constructs. It does not recognize antigens in COS-7 cells transfected with dysbindin-2 expression constructs. (
B) The antibody M10RP-FLA (1:50) recognizes dysbindin-2, which is of lower molecular weight than dysbindin-1. (
C) Equal loading of samples was demonstrated with β-tubulin antibody T4026 from Sigma-Aldrich (1:5,000).