Methylguanine methyltransferase–mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model
J. Clin. Invest. Tobias Neff, et al. 112:1581 doi:10.1172/JCI18782 [Go to this article.]

Figure 2
In vivo selection in dog G154 after three cycles of O6BG and BCNU. (a–c) Flow-cytometric analysis. (a) Percent EGFP-positive granulocytes (open circles) and lymphocytes (filled squares) from peripheral blood. (b) Percent EGFP-positive red blood cells (open circles) and platelets (filled squares) from peripheral blood. (c) Percent EGFP-positive CD34+ cells from bone marrow (open circles). (d) Platelet counts in the peripheral blood over time. The arrows indicate the three cycles of drug administration.