Randall’s plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle
J. Clin. Invest. Andrew P. Evan, et al. 111:607 doi:10.1172/JCI17038 [Go to this article.]

Figure 3
Crystalline deposits on interstitial collagen. In (a) and (b), numerous sites of crystal deposition are shown (green arrows) on the interstitial collagen located between the loops of Henle and nearby vascular bundles in the papillary tissue of a CaOx patient. The inset in (b) illustrates the relationship of the initial small sites of crystal formation on individual collagen fibers at a higher magnification. In (c) and (d), a progressive accumulation of crystal deposition (green arrows) is shown in the interstitium near the loops of Henle. Magnification, ×650 (a); ×4,750 (b); ×16,500 (inset in b); ×900 (c); ×3,900 (d).