Reversal of established autoimmune diabetes by restoration of endogenous β cell function
J. Clin. Invest. Shinichiro Ryu, et al. 108:63 doi:10.1172/JCI12335 [
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Figure 3Blood glucose concentrations (left panels) and histology of the pancreata (right panels) of diabetic NOD female mice treated with CFA and intrarenal transplantation of islets from
β2M–/– C57 mice. The kidneys containing the islet grafts were removed at the times after transplantation indicated by the arrows. The animals were killed at various times thereafter, and the pancreata were subjected to histological staining with hematoxylin and eosin. Representative islets are shown. ×400.
