Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
J. Clin. Invest. Albert S. Baldwin, et al. 107:241 doi:10.1172/JCI11991 [
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Figure 2Roles of NF-κB in oncogenesis and in cancer chemo- and radioresistance. Activation of NF-κB blocks apoptosis, induces cell proliferation, potentially blocks differentiation, and promotes metastasis.